THE BASIC PRINCIPLES OF LACHGAS

The last proposed mechanism of RBC vasodilation during the presence of nitrite will be the reduction of nitrite to NO by Hb. Brooks to start with studied the nitrite Hb interaction in 1937 which do the job was later on prolonged by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to kind metHb and NO (Brooks, 19